High adenoviral vector concentration can cause irreversible aggregation during CsCl gradient ultracentrifugation
Highly purified adenovirus preparations are essential for fundamental research and therapeutic use. However, the impact of viral concentration during CsCl gradient ultracentrifugation on virion integrity is poorly understood, and this incomplete mechanistic understanding may adversely affect product...
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| Autori principali: | , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Frontiers Media S.A.
2026-06-01
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| Serie: | Frontiers in Microbiology |
| Soggetti: | |
| Accesso online: | https://www.frontiersin.org/articles/10.3389/fmicb.2026.1845210/full |
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