Allosteric Inhibition of Adenylyl Cyclase Type 5 by G-Protein: A Molecular Dynamics Study

Adenylyl cyclases (ACs) have a crucial role in many signal transduction pathways, in particular in the intricate control of cyclic AMP (cAMP) generation from adenosine triphosphate (ATP). Using homology models developed from existing structural data and docking experiments, we have carried out all-a...

Cijeli opis

Bibliografski detalji

Glavni autori:	Elisa Frezza, Tina-Méryl Amans, Juliette Martin
Format:	Artigo
Jezik:	Inglês
Izdano:	MDPI AG 2020-09-01
Serija:	Biomolecules
Teme:	molecular dynamics flexibility protein-protein interactions allostery enzyme activity docking
Online pristup:	https://www.mdpi.com/2218-273X/10/9/1330
Oznake:	Dodaj oznaku Bez oznaka, Budi prvi tko označuje ovaj zapis!