Characterization of Cysteine Cathepsin Expression in the Central Nervous System of Aged Wild-Type and Cathepsin-Deficient Mice

The association of cathepsin proteases in neurobiology is increasingly recognized. Our previous studies indicated that cathepsin-K-deficient (<i>Ctsk</i>^−/−) mice have learning and memory impairments. Alterations in cathepsin expression are known to result in compensatory changes in level...

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Principais autores:	Denise M. T. Yu, Stephanie Dauth, Michael B. Margineanu, Valentina Snetkova, Maren Rehders, Silvia Jordans, Klaudia Brix
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2022-03-01
coleção:	Applied Sciences
Assuntos:	aging disorders aspartic proteases brain cystatin C cysteine peptidases protease inhibitor therapy
Acesso em linha:	https://www.mdpi.com/2076-3417/12/5/2608
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