Impact of drug distribution into adipose on tissue function: The cholesteryl ester transfer protein (CETP) inhibitor anacetrapib as a test case

Abstract Anacetrapib is an inhibitor of cholesteryl ester transfer protein (CETP) previously under development as a lipid‐modifying agent that reduces LDL‐cholesterol and increases HDL‐cholesterol in hypercholesterolemic patients. Anacetrapib demonstrates a long terminal half‐life and accumulates in...

詳細記述

書誌詳細

主要な著者:	Douglas G. Johns, Sheng‐Ping Wang, Raymond Rosa, James Hubert, Suoyu Xu, Ying Chen, Thomas Bateman, Robert O. Blaustein
フォーマット:	Artigo
言語:	Inglês
出版事項:	Wiley 2019-12-01
シリーズ:	Pharmacology Research & Perspectives
主題:	adipose anacetrapib cholesteryl ester transfer protein pharmacokinetics
オンライン･アクセス:	https://doi.org/10.1002/prp2.543
タグ:	タグ追加 タグなし, このレコードへの初めてのタグを付けませんか!