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Mechanistically Explainable AI Model for Predicting Synergistic Cancer Therapy Combinations

This study introduces a Large Language Model (LLM)-based framework that combines drug combination data with a knowledge graph to predict synergistic oncology drug combinations with mechanistic insights. Using a retrieval-augmented generation (RAG) approach, over 50,000 in vitro drug pair assay resul...

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Detaylı Bibliyografya
Asıl Yazarlar: Han Si, Sanyam Kumar, Sneh Lata, Arshad Ahmad, Saurav Ghosh, Karen Stephansen, Deepti Nagarkar, Eda Zhou, Brandon W. Higgs
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: MDPI AG 2025-09-01
Seri Bilgileri:Current Oncology
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Online Erişim:https://www.mdpi.com/1718-7729/32/10/548
Etiketler: Etiketle
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