Matrine Directly Activates Extracellular Heat Shock Protein 90, Resulting in Axonal Growth and Functional Recovery in Spinal Cord Injured-Mice

After spinal cord injury (SCI), reconstruction of neuronal tracts is very difficult because an inhibitory scar is formed at the lesion site, in which several axonal growth inhibitors, such as chondroitin sulfate proteoglycans (CSPG), accumulate. We previously found that matrine, a major alkaloid in...

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Үндсэн зохиолчид:	Norio Tanabe, Tomoharu Kuboyama, Chihiro Tohda
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Frontiers Media S.A. 2018-05-01
Цуврал:	Frontiers in Pharmacology
Нөхцлүүд:	matrine spinal cord injury axonal growth chondroitin sulfate proteoglycan DARTS heat shock protein 90
Онлайн хандалт:	http://journal.frontiersin.org/article/10.3389/fphar.2018.00446/full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!