Sphingosylphosphorylcholine inhibits plasma cell differentiation and ameliorates experimental autoimmune encephalomyelitis

IntroductionMultiple sclerosis (MS) is a potentially disabling disease that damages the brain and spinal cord, inducing paralysis of the body. While MS has been known as a T-cell mediated disease, recent attention has been drawn to the involvement of B cells in its pathogenesis. Autoantibodies from...

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Autores principales:	Byunghyun Park, Yu Sun Jeong, Wonseok Hu, Mingyu Lee, Ji Cheol Kim, Geon Ho Bae, Yong-Soo Bae, Yoe-Sik Bae
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2023-06-01
Colección:	Frontiers in Immunology
Materias:	sphingosylphosphorylcholine plasma cells S1PR3 experimental autoimmune encephalomyelitis multiple sclerosis
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1151511/full
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