Sphingosylphosphorylcholine inhibits plasma cell differentiation and ameliorates experimental autoimmune encephalomyelitis

IntroductionMultiple sclerosis (MS) is a potentially disabling disease that damages the brain and spinal cord, inducing paralysis of the body. While MS has been known as a T-cell mediated disease, recent attention has been drawn to the involvement of B cells in its pathogenesis. Autoantibodies from...

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Autori principali:	Byunghyun Park, Yu Sun Jeong, Wonseok Hu, Mingyu Lee, Ji Cheol Kim, Geon Ho Bae, Yong-Soo Bae, Yoe-Sik Bae
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Frontiers Media S.A. 2023-06-01
Serie:	Frontiers in Immunology
Soggetti:	sphingosylphosphorylcholine plasma cells S1PR3 experimental autoimmune encephalomyelitis multiple sclerosis
Accesso online:	https://www.frontiersin.org/articles/10.3389/fimmu.2023.1151511/full
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