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Discovery and Early Clinical Development of Selective Immunoproteasome Inhibitors

Inhibitors of the proteolytic activity of the 20S proteasome have transformed the treatment of multiple B-cell malignancies. These agents have also been employed with success in the treatment of patients with autoimmune diseases and immune-mediated disorders. However, new agents are needed to fully...

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Bibliografische gegevens
Hoofdauteurs: Christopher J. Kirk, Tony Muchamuel, Jinhai Wang, R. Andrea Fan
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI AG 2021-12-01
Reeks:Cells
Onderwerpen:
Online toegang:https://www.mdpi.com/2073-4409/11/1/9
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