Functional ADAM12 variants modulate proteolytic activity and influence metabolic traits

Abstract The high prevalence of insulin resistance and metabolic syndrome in Kuwait increases the risk of type 2 diabetes (T2D) and cardiovascular diseases development. Although the genetic contribution to insulin resistance and metabolic syndrome is established, the role of a disintegrin and metall...

Full description

Bibliographic Details

Main Authors:	Hana Drobiova, Ashraf Al Madhoun, Thangavel Alphonse Thanaraj, Arshad Channanath, Prashantha Hebbar, Sardar Sindhu, Rasheed Ahmad, Fahd Al-Mulla, Rabeah Al-Temaimi
Format:	Artigo
Language:	Inglês
Published:	Nature Portfolio 2026-01-01
Series:	Scientific Reports
Subjects:	ADAM12 Metabolic syndrome Insulin resistance Genetic variant
Online Access:	https://doi.org/10.1038/s41598-025-34827-1
Tags:	Add Tag No Tags, Be the first to tag this record!