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Synthesis and Evaluation of Reactive Oxygen Species Sensitive Prodrugs of a NAMPT Inhibitor FK866

NAMPT is an attractive target in cancer therapy and numerous NAMPT inhibitors have been developed. However, the clinical activities of NAMPT inhibitors have displayed disappointing results in clinical trials for their dose-limiting toxicities. In this study, reactive oxygen species (ROS)-responsive...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zili Xu, Huihui Wang, Haixia Liu, Hongli Chen, Biao Jiang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI AG 2022-12-01
Cyfres:Molecules
Pynciau:
Mynediad Ar-lein:https://www.mdpi.com/1420-3049/28/1/169
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!