The Fluorinated NAD Precursors Enhance FK866 Cytotoxicity by Activating SARM1 in Glioblastoma Cells
Glioblastoma, a formidable brain tumor characterized by dysregulated NAD metabolism, poses a significant therapeutic challenge. The NAMPT inhibitor FK866, which induces NAD depletion, has shown promise in controlling tumor proliferation and modifying the tumor microenvironment. However, the clinical...
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| Format: | Artigo |
| Sprache: | Inglês |
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MDPI AG
2024-08-01
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| Schriftenreihe: | Biology |
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| Online-Zugang: | https://www.mdpi.com/2079-7737/13/9/649 |
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