The nicotinamide phosphoribosyltransferase inhibitor FK866 restricts influenza A virus replication by perturbing viral polymerase activity
ABSTRACT Nicotinamide phosphoribosyltransferase (NAMPT), a key rate-limiting enzyme in NAD+ synthesis, plays important roles in various physiological and pathological processes. However, the function and underlying mechanisms of NAMPT in influenza A virus (IAV) infection and pathogenesis remain ambi...
שמור ב:
| Principais autores: | , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
American Society for Microbiology
2026-07-01
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| סדרה: | Journal of Virology |
| נושאים: | |
| גישה מקוונת: | https://journals.asm.org/doi/10.1128/jvi.00591-26 |
| תגים: |
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