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The Fluorinated NAD Precursors Enhance FK866 Cytotoxicity by Activating SARM1 in Glioblastoma Cells

Glioblastoma, a formidable brain tumor characterized by dysregulated NAD metabolism, poses a significant therapeutic challenge. The NAMPT inhibitor FK866, which induces NAD depletion, has shown promise in controlling tumor proliferation and modifying the tumor microenvironment. However, the clinical...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Wei Ming He, Jian Yuan Yang, Zhi Ying Zhao, Weimin Xiao, Wan Hua Li, Yong Juan Zhao
Hōputu: Artigo
Reo:Inglês
I whakaputaina: MDPI AG 2024-08-01
Rangatū:Biology
Ngā marau:
Urunga tuihono:https://www.mdpi.com/2079-7737/13/9/649
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