Tyrosine kinase LYN restricts the replication and virulence of influenza A virus by directly phosphorylating viral nucleoprotein

ABSTRACT The continuous antigenic shift and drift of influenza A virus (IAV) result in the emergence of novel strains and drug resistance. Accordingly, it is urgent to develop novel antiviral drugs that target host factors. Here, we revealed that tyrosine kinase LYN (Lck/Yes-related novel protein ty...

Celý popis

Podrobná bibliografie

Hlavní autoři:	Junwen Liu, Jiaxin Huang, Qian Wang, Yanli Wei, Lebin Han, Xin Li, Caoqi Lei, Guohua Deng, Hualan Chen, Qiyun Zhu, Shuai Xu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2026-05-01
Edice:	mBio
Témata:	influenza A virus LYN tyrosine kinase phosphorylation nucleoprotein
On-line přístup:	https://journals.asm.org/doi/10.1128/mbio.03759-25
Tagy:	Přidat tag Žádné tagy, Buďte první, kdo vytvoří štítek k tomuto záznamu!