Broad-spectrum inhibition of influenza A virus replication by blocking the nuclear export of viral ribonucleoprotein complexes

ABSTRACT Influenza A virus (IAV) remains a major threat to global health. The emergence of IAV strains resistant to commonly used anti-influenza medicines has made the need for novel broad-spectrum antiviral agents more urgent. The IAV nucleoprotein (NP) is one of the most conserved viral proteins e...

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Hlavní autoři:	Wentao Shen, Jie Xu, Zhaoshan Chen, Yanli Wei, Qian Wang, Xiangkun Wang, Xuegang Zhang, Qiyun Zhu, Shuai Xu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	American Society for Microbiology 2025-12-01
Edice:	Journal of Virology
Témata:	influenza A viruses nanobody nucleoprotein nuclear export viral replication
On-line přístup:	https://journals.asm.org/doi/10.1128/jvi.01478-25
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