Tyrosine kinase LYN restricts the replication and virulence of influenza A virus by directly phosphorylating viral nucleoprotein

ABSTRACT The continuous antigenic shift and drift of influenza A virus (IAV) result in the emergence of novel strains and drug resistance. Accordingly, it is urgent to develop novel antiviral drugs that target host factors. Here, we revealed that tyrosine kinase LYN (Lck/Yes-related novel protein ty...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Junwen Liu, Jiaxin Huang, Qian Wang, Yanli Wei, Lebin Han, Xin Li, Caoqi Lei, Guohua Deng, Hualan Chen, Qiyun Zhu, Shuai Xu
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	American Society for Microbiology 2026-05-01
Цуврал:	mBio
Нөхцлүүд:	influenza A virus LYN tyrosine kinase phosphorylation nucleoprotein
Онлайн хандалт:	https://journals.asm.org/doi/10.1128/mbio.03759-25
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!