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Abnormal Ergosterol Biosynthesis Activates Transcriptional Responses to Antifungal Azoles

Fungi transcriptionally upregulate expression of azole efflux pumps and ergosterol biosynthesis pathway genes when exposed to antifungal agents that target ergosterol biosynthesis. To date, these transcriptional responses have been shown to be dependent on the presence of the azoles and/or depletion...

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Principais autores: Chengcheng Hu, Mi Zhou, Wenzhao Wang, Xianyun Sun, Oded Yarden, Shaojie Li
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018-01-01
Serija:Frontiers in Microbiology
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Online dostop:http://journal.frontiersin.org/article/10.3389/fmicb.2018.00009/full
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