Abnormal Ergosterol Biosynthesis Activates Transcriptional Responses to Antifungal Azoles

Fungi transcriptionally upregulate expression of azole efflux pumps and ergosterol biosynthesis pathway genes when exposed to antifungal agents that target ergosterol biosynthesis. To date, these transcriptional responses have been shown to be dependent on the presence of the azoles and/or depletion...

Description complète

Détails bibliographiques

Auteurs principaux:	Chengcheng Hu, Mi Zhou, Wenzhao Wang, Xianyun Sun, Oded Yarden, Shaojie Li
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2018-01-01
Collection:	Frontiers in Microbiology
Sujets:	azoles stress response sterol 14α-demethylase C-8 sterol isomerase efflux pump sterol intermediate
Accès en ligne:	http://journal.frontiersin.org/article/10.3389/fmicb.2018.00009/full
Tags:	Ajouter un tag Pas de tags, Soyez le premier à ajouter un tag!