Abnormal Ergosterol Biosynthesis Activates Transcriptional Responses to Antifungal Azoles

Fungi transcriptionally upregulate expression of azole efflux pumps and ergosterol biosynthesis pathway genes when exposed to antifungal agents that target ergosterol biosynthesis. To date, these transcriptional responses have been shown to be dependent on the presence of the azoles and/or depletion...

Descripción completa

Detalles Bibliográficos

Autores principales:	Chengcheng Hu, Mi Zhou, Wenzhao Wang, Xianyun Sun, Oded Yarden, Shaojie Li
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2018-01-01
Colección:	Frontiers in Microbiology
Materias:	azoles stress response sterol 14α-demethylase C-8 sterol isomerase efflux pump sterol intermediate
Acceso en línea:	http://journal.frontiersin.org/article/10.3389/fmicb.2018.00009/full
Etiquetas:	Agregar Etiqueta Sin Etiquetas, Sea el primero en etiquetar este registro!