AST-120 alleviates renal ischemia-reperfusion injury by inhibiting HK2-mediated glycolysis

Abstract Objective Renal ischemia/reperfusion injury (IRI) is a major cause of acute kidney injury (AKI), which is associated with high incidence and mortality. AST-120 is an oral carbonaceous adsorbent that can alleviate kidney damage. This study aimed to explore the effects of AST-120 on renal IRI...

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Váldodahkkit:	Jinmeng Zhou, Jinbao Zhang, Feng Xu, Haijin Gao, Lei Wang, Yutong Zhao, Ke Li
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	BMC 2024-08-01
Ráidu:	Molecular Medicine
Fáttát:	Renal ischemia-reperfusion injury AST-120 Glycolysis HK2 Histone lactylation
Liŋkkat:	https://doi.org/10.1186/s10020-024-00902-y
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