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AST-120 alleviates renal ischemia-reperfusion injury by inhibiting HK2-mediated glycolysis

Abstract Objective Renal ischemia/reperfusion injury (IRI) is a major cause of acute kidney injury (AKI), which is associated with high incidence and mortality. AST-120 is an oral carbonaceous adsorbent that can alleviate kidney damage. This study aimed to explore the effects of AST-120 on renal IRI...

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Principais autores: Jinmeng Zhou, Jinbao Zhang, Feng Xu, Haijin Gao, Lei Wang, Yutong Zhao, Ke Li
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2024-08-01
Series:Molecular Medicine
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Acceso en liña:https://doi.org/10.1186/s10020-024-00902-y
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