Glycolytic reprogramming governs crystalline silica-induced pyroptosis and inflammation through promoting lactylation modification

Prolonged inhalation of environmental crystalline silica (CS) can cause silicosis, characterized by persistent pulmonary inflammation and irreversible fibrosis, but the mechanism has not been elucidated. To uncover the role and underlying mechanism of glycolytic reprogramming in CS-induced pulmonary...

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Hlavní autoři:	Xiaojie You, Yujia Xie, Qiyou Tan, Chao Zhou, Pei Gu, Yingdie Zhang, Shiyu Yang, Haoyu Yin, Bingxin Shang, Yuxin Yao, Dongming Wang, Jixuan Ma, Weihong Chen, Xiaoju Zhang
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2024-09-01
Edice:	Ecotoxicology and Environmental Safety
Témata:	Crystalline silica Glycolytic reprogramming Lactate Lactylation Pyroptosis Lung inflammation
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S0147651324010285
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