Glycolytic reprogramming governs crystalline silica-induced pyroptosis and inflammation through promoting lactylation modification

Prolonged inhalation of environmental crystalline silica (CS) can cause silicosis, characterized by persistent pulmonary inflammation and irreversible fibrosis, but the mechanism has not been elucidated. To uncover the role and underlying mechanism of glycolytic reprogramming in CS-induced pulmonary...

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मुख्य लेखकों:	Xiaojie You, Yujia Xie, Qiyou Tan, Chao Zhou, Pei Gu, Yingdie Zhang, Shiyu Yang, Haoyu Yin, Bingxin Shang, Yuxin Yao, Dongming Wang, Jixuan Ma, Weihong Chen, Xiaoju Zhang
स्वरूप:	Artigo
भाषा:	Inglês
प्रकाशित:	Elsevier 2024-09-01
श्रृंखला:	Ecotoxicology and Environmental Safety
विषय:	Crystalline silica Glycolytic reprogramming Lactate Lactylation Pyroptosis Lung inflammation
ऑनलाइन पहुंच:	http://www.sciencedirect.com/science/article/pii/S0147651324010285
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