A six-gene expression signature in peripheral blood mononuclear cells effectively diagnoses osteoarthritis

IntroductionOsteoarthritis (OA) is a heterogeneous whole-joint disease that inconveniences more than 500 million people worldwide. Early diagnostic methods for OA remain lacking. Peripheral blood mononuclear cells (PBMCs) are ideal sample sources for the early diagnosis of different diseases. Howeve...

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Autores principales:	Dong Yu, Wei Ding, Xiuru Xue, Zheng Zhang, Jinchang Meng, Bin Yang, Chunlin Liang, Guanghui Zhao, Xiangmao Bu, Wei Chen
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Frontiers Media S.A. 2025-10-01
Colección:	Frontiers in Medicine
Materias:	osteoarthritis PBMC RNA sequencing diagnostic model expression signature
Acceso en línea:	https://www.frontiersin.org/articles/10.3389/fmed.2025.1632348/full
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