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Impact of Isolation Procedures on the Development of a Preclinical Synovial Fibroblasts/Macrophages in an In Vitro Model of Osteoarthritis

There is a lack ofin vitromodels able to properly represent osteoarthritis (OA) synovial tissue (ST). We aimed to characterize OA ST and to investigate whether a mechanical or enzymatic digestion procedures influence synovial cell functional heterogeneity in vitro. Procedures using mechanical nondig...

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Principais autores: Cristina Manferdini, Yasmin Saleh, Paolo Dolzani, Elena Gabusi, Diego Trucco, Giuseppe Filardo, Gina Lisignoli
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2020-12-01
Serier:Biology
Fag:
synovial cells
synovial macrophages
synovial fibroblasts
isolation methods
osteoarthritis
Online adgang:https://www.mdpi.com/2079-7737/9/12/459
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