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Chondrocyte primary cilia lengthening and shortening in response to mediators of osteoarthritis; a role for integrin α1β1 and focal adhesions

Objective: Integrin α1β1 protects against osteoarthritis when it is upregulated in the early stages of disease, however, the mechanism behind this is currently unknown. Hypo-osmotic stress, interleukin-1 (IL-1) and transforming growth factor β (TGFβ) influence chondrocyte signaling and are important...

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מידע ביבליוגרפי
Principais autores: Lauren B. Stam, Andrea L. Clark
פורמט: Artigo
שפה:Inglês
יצא לאור: Elsevier 2023-06-01
סדרה:Osteoarthritis and Cartilage Open
נושאים:
גישה מקוונת:http://www.sciencedirect.com/science/article/pii/S2665913123000249
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