Polypeptide-Based Molecular Platform and Its Docetaxel/Sulfo-Cy5-Containing Conjugate for Targeted Delivery to Prostate Specific Membrane Antigen

A strategy for stereoselective synthesis of molecular platform for targeted delivery of bimodal therapeutic or theranostic agents to the prostate-specific membrane antigen (PSMA) receptor was developed. The proposed platform contains a urea-based, PSMA-targeting Glu-Urea-Lys (EuK) fragment as a vect...

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Auteurs principaux:	Stanislav A. Petrov, Aleksei E. Machulkin, Anastasia A. Uspenskaya, Nikolay Y. Zyk, Ekaterina A. Nimenko, Anastasia S. Garanina, Rostislav A. Petrov, Vladimir I. Polshakov, Yuri K. Grishin, Vitaly A. Roznyatovsky, Nikolay V. Zyk, Alexander G. Majouga, Elena K. Beloglazkina
Format:	Artigo
Langue:	Inglês
Publié:	MDPI AG 2020-12-01
Collection:	Molecules
Sujets:	theranostic agent peptide synthesis prostate cancer anticancer drugs PSMA conjugate docetaxel
Accès en ligne:	https://www.mdpi.com/1420-3049/25/24/5784
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