Polypeptide-Based Molecular Platform and Its Docetaxel/Sulfo-Cy5-Containing Conjugate for Targeted Delivery to Prostate Specific Membrane Antigen

A strategy for stereoselective synthesis of molecular platform for targeted delivery of bimodal therapeutic or theranostic agents to the prostate-specific membrane antigen (PSMA) receptor was developed. The proposed platform contains a urea-based, PSMA-targeting Glu-Urea-Lys (EuK) fragment as a vect...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Stanislav A. Petrov, Aleksei E. Machulkin, Anastasia A. Uspenskaya, Nikolay Y. Zyk, Ekaterina A. Nimenko, Anastasia S. Garanina, Rostislav A. Petrov, Vladimir I. Polshakov, Yuri K. Grishin, Vitaly A. Roznyatovsky, Nikolay V. Zyk, Alexander G. Majouga, Elena K. Beloglazkina
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2020-12-01
Schriftenreihe:	Molecules
Schlagworte:	theranostic agent peptide synthesis prostate cancer anticancer drugs PSMA conjugate docetaxel
Online-Zugang:	https://www.mdpi.com/1420-3049/25/24/5784
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!