Deubiquitination-related genes define immune subtypes of colorectal cancer and are associated with prognosis and immunotherapy-related signatures

Abstract Colorectal cancer (CRC) is highly heterogeneous, and the contribution of deubiquitination (DUB) programs to immune context and clinical outcome remains incompletely defined. We integrated transcriptomes from TCGA and GTEx (COAD/READ) with an external GEO cohort (GSE39582) to delineate DUB-a...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Yiwei Xu, Zhiyong Mo, Qing Jiang, Jingjing Pan, Qi Xu, Juwen Jia
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	Nature Portfolio 2026-01-01
Цуврал:	Scientific Reports
Нөхцлүүд:	Colorectal cancer Deubiquitination Molecular subtypes Immune microenvironment Immunotherapy Prognostic biomarkers
Онлайн хандалт:	https://doi.org/10.1038/s41598-026-35271-5
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!