Deubiquitination-related genes define immune subtypes of colorectal cancer and are associated with prognosis and immunotherapy-related signatures

Abstract Colorectal cancer (CRC) is highly heterogeneous, and the contribution of deubiquitination (DUB) programs to immune context and clinical outcome remains incompletely defined. We integrated transcriptomes from TCGA and GTEx (COAD/READ) with an external GEO cohort (GSE39582) to delineate DUB-a...

Täydet tiedot

Bibliografiset tiedot

Päätekijät:	Yiwei Xu, Zhiyong Mo, Qing Jiang, Jingjing Pan, Qi Xu, Juwen Jia
Aineistotyyppi:	Artigo
Kieli:	Inglês
Julkaistu:	Nature Portfolio 2026-01-01
Sarja:	Scientific Reports
Aiheet:	Colorectal cancer Deubiquitination Molecular subtypes Immune microenvironment Immunotherapy Prognostic biomarkers
Linkit:	https://doi.org/10.1038/s41598-026-35271-5
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