Deubiquitination-related genes define immune subtypes of colorectal cancer and are associated with prognosis and immunotherapy-related signatures

Abstract Colorectal cancer (CRC) is highly heterogeneous, and the contribution of deubiquitination (DUB) programs to immune context and clinical outcome remains incompletely defined. We integrated transcriptomes from TCGA and GTEx (COAD/READ) with an external GEO cohort (GSE39582) to delineate DUB-a...

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Λεπτομέρειες βιβλιογραφικής εγγραφής

Κύριοι συγγραφείς:	Yiwei Xu, Zhiyong Mo, Qing Jiang, Jingjing Pan, Qi Xu, Juwen Jia
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Nature Portfolio 2026-01-01
Σειρά:	Scientific Reports
Θέματα:	Colorectal cancer Deubiquitination Molecular subtypes Immune microenvironment Immunotherapy Prognostic biomarkers
Διαθέσιμο Online:	https://doi.org/10.1038/s41598-026-35271-5
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