Mycobacterium tuberculosis uses intrinsically disordered, fast evolving proteins to interact with conserved host factors

Abstract Background Intrinsically disordered protein regions (IDRs) are implicated in diverse cellular processes in eukaryotes and, in these organisms, they cover up to 40% of the proteome. Surprisingly little is known about IDRs in bacterial proteomes. Specifically, a number of questions remain una...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Uberto Pozzoli, Diego Forni, Federica Arrigoni, Rachele Cagliani, Luca De Gioia, Manuela Sironi
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	BMC 2025-11-01
سلاسل:	Genome Biology
الموضوعات:	Mycobacterium tuberculosis Intrinsically disordered protein regions Host–pathogen interaction Evolution Conformational features Bacterial proteomes
الوصول للمادة أونلاين:	https://doi.org/10.1186/s13059-025-03854-6
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!