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A Programmable Eukaryotic Argonaute Nuclease with Dual DNA and RNA Cleavage Activity from Thermophilic Fungus Thermochaetoides thermophila

Eukaryotic Argonautes (eAgos) are well‐known for their role in utilizing RNA guides to recognize and cleave RNA targets, thereby participating in posttranscriptional regulation and RNA interference. However, it remains unclear whether certain eAgos can also cleave DNA at mesophilic temperatures. Her...

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Hlavní autoři: Zhizhao Chen, Fei Wang, Xiaolan Yu, Yang Liu, Lixin Ma
Médium: Artigo
Jazyk:Inglês
Vydáno: Wiley-VCH 2026-03-01
Edice:Small Science
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On-line přístup:https://doi.org/10.1002/smsc.202500237
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