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A Programmable Eukaryotic Argonaute Nuclease with Dual DNA and RNA Cleavage Activity from Thermophilic Fungus Thermochaetoides thermophila

Eukaryotic Argonautes (eAgos) are well‐known for their role in utilizing RNA guides to recognize and cleave RNA targets, thereby participating in posttranscriptional regulation and RNA interference. However, it remains unclear whether certain eAgos can also cleave DNA at mesophilic temperatures. Her...

詳細記述

保存先:
書誌詳細
主要な著者: Zhizhao Chen, Fei Wang, Xiaolan Yu, Yang Liu, Lixin Ma
フォーマット: Artigo
言語:Inglês
出版事項: Wiley-VCH 2026-03-01
シリーズ:Small Science
主題:
オンライン・アクセス:https://doi.org/10.1002/smsc.202500237
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