Divergence in a eukaryotic transcription factor’s co-TF dependence involves multiple intrinsically disordered regions

Abstract Combinatorial control by transcription factors (TFs) is central to eukaryotic gene regulation, yet its mechanism, evolution, and regulatory impact are not well understood. Here we use natural variation in the yeast phosphate starvation (PHO) response to examine the genetic basis and species...

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Autores principales:	Lindsey F. Snyder, Emily M. O’Brien, Jia Zhao, Jinye Liang, Baylee J. Bruce, Yuning Zhang, Wei Zhu, Thomas H. Cassier, Nicholas J. Schnicker, Xu Zhou, Raluca Gordân, Bin Z. He
Formato:	Artigo
Lenguaje:	Inglês
Publicado:	Nature Portfolio 2025-06-01
Colección:	Nature Communications
Acceso en línea:	https://doi.org/10.1038/s41467-025-59244-w
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