Divergence in a eukaryotic transcription factor’s co-TF dependence involves multiple intrinsically disordered regions

Abstract Combinatorial control by transcription factors (TFs) is central to eukaryotic gene regulation, yet its mechanism, evolution, and regulatory impact are not well understood. Here we use natural variation in the yeast phosphate starvation (PHO) response to examine the genetic basis and species...

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Principais autores:	Lindsey F. Snyder, Emily M. O’Brien, Jia Zhao, Jinye Liang, Baylee J. Bruce, Yuning Zhang, Wei Zhu, Thomas H. Cassier, Nicholas J. Schnicker, Xu Zhou, Raluca Gordân, Bin Z. He
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Nature Portfolio 2025-06-01
סדרה:	Nature Communications
גישה מקוונת:	https://doi.org/10.1038/s41467-025-59244-w
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