Mineralocorticoid receptor antagonists and glucocorticoids differentially affect skeletal muscle inflammation and pathology in muscular dystrophy

Mineralocorticoid receptor antagonists (MRAs) slow cardiomyopathy in patients with Duchenne muscular dystrophy (DMD) and improve skeletal muscle pathology and function in dystrophic mice. However, glucocorticoids, known antiinflammatory drugs, remain a standard of care for DMD, despite substantial s...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Zachary M. Howard, Chetan K. Gomatam, Charles P. Rabolli, Jeovanna Lowe, Arden B. Piepho, Shyam S. Bansal, Federica Accornero, Jill A. Rafael-Fortney
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	American Society for Clinical investigation 2022-10-01
Schriftenreihe:	JCI Insight
Schlagworte:	Muscle biology
Online-Zugang:	https://doi.org/10.1172/jci.insight.159875
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!