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Direct aldosterone stimulation of skeletal muscle fibroblasts changes gene expression and differentially affects fibroblast functions from normal and diseased muscles

IntroductionFibroblasts are critical for stabilizing skeletal muscle and facilitating wound healing after injury but become overactivated and lead to fibrotic replacement of muscle tissue in chronic degenerative diseases such as Duchenne muscular dystrophy (DMD). We have previously shown that the mi...

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Bibliografiset tiedot
Päätekijät: Chetan K. Gomatam, Swathy Krishna, Jeovanna Lowe, Esther Silver, Christoph Lepper, Jill A. Rafael-Fortney
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Frontiers Media S.A. 2026-04-01
Sarja:Frontiers in Physiology
Aiheet:
Linkit:https://www.frontiersin.org/articles/10.3389/fphys.2026.1760238/full
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