Conjugation of Doxorubicin to siRNA Through Disulfide-based Self-immolative Linkers

Co-delivery systems of siRNA and chemotherapeutic drugs have been developed as an attractive strategy to optimize the efficacy of chemotherapy towards cancer cells with multidrug resistance. In these typical systems, siRNAs are usually associated to drugs within a carrier but without covalent intera...

תיאור מלא

מידע ביבליוגרפי

Principais autores:	Florian Gauthier, Jean-Rémi Bertrand, Jean-Jacques Vasseur, Christelle Dupouy, Françoise Debart
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	MDPI AG 2020-06-01
סדרה:	Molecules
נושאים:	doxorubicin siRNA conjugation disulfide bond self-immolative linker thiol-disulfide exchange
גישה מקוונת:	https://www.mdpi.com/1420-3049/25/11/2714
תגים:	הוספת תג אין תגיות, היה/י הראשונ/ה לתייג את הרשומה!