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Conjugation of Doxorubicin to siRNA Through Disulfide-based Self-immolative Linkers

Co-delivery systems of siRNA and chemotherapeutic drugs have been developed as an attractive strategy to optimize the efficacy of chemotherapy towards cancer cells with multidrug resistance. In these typical systems, siRNAs are usually associated to drugs within a carrier but without covalent intera...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Florian Gauthier, Jean-Rémi Bertrand, Jean-Jacques Vasseur, Christelle Dupouy, Françoise Debart
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: MDPI AG 2020-06-01
Cyfres:Molecules
Pynciau:
Mynediad Ar-lein:https://www.mdpi.com/1420-3049/25/11/2714
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!