From Powerhouse to Perpetrator—Mitochondria in Health and Disease

In this review we discuss the interaction between metabolic stress, mitochondrial dysfunction, and genomic instability. Unrepaired DNA damage in the nucleus resulting from excess accumulation of DNA damages and stalled replication can initiate cellular signaling responses that negatively affect meta...

Бүрэн тодорхойлолт

Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	Nima B. Fakouri, Thomas Lau Hansen, Claus Desler, Sharath Anugula, Lene Juel Rasmussen
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	MDPI AG 2019-05-01
Цуврал:	Biology
Нөхцлүүд:	mitochondria cancer nucleotide metabolism DNA damage NAD<sup>+</sup>
Онлайн хандалт:	https://www.mdpi.com/2079-7737/8/2/35
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!