From Powerhouse to Perpetrator—Mitochondria in Health and Disease

In this review we discuss the interaction between metabolic stress, mitochondrial dysfunction, and genomic instability. Unrepaired DNA damage in the nucleus resulting from excess accumulation of DNA damages and stalled replication can initiate cellular signaling responses that negatively affect meta...

詳細記述

書誌詳細

主要な著者:	Nima B. Fakouri, Thomas Lau Hansen, Claus Desler, Sharath Anugula, Lene Juel Rasmussen
フォーマット:	Artigo
言語:	Inglês
出版事項:	MDPI AG 2019-05-01
シリーズ:	Biology
主題:	mitochondria cancer nucleotide metabolism DNA damage NAD<sup>+</sup>
オンライン･アクセス:	https://www.mdpi.com/2079-7737/8/2/35
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