Low tumoral Trefoil Factor 1 expression relates to aggressive tumor features and poor survival in young women with breast cancer

Abstract In young breast cancer (BC) patients, there is a need for additional biomarkers beyond those currently available. Trefoil Factor 1 (TFF1) is an estrogen-regulated protein with proposed prognostic relevance in BC. We assessed TFF1 protein expression by immunohistochemistry (IHC) in biopsies...

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Autors principals:	Amalie B. Kvamme, Ulrikke Hugaas, Anna K. M. Sæle, Lise M. Ingebriktsen, Amalie A. Svanøe, Rasmus O. C. Humlevik, Ingeborg Winge, Turid Aas, Anette Heie, Lars A. Akslen, Erling A. Hoivik, Elisabeth Wik
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2026-01-01
Col·lecció:	Scientific Reports
Matèries:	Breast cancer TFF1 Young age Survival
Accés en línia:	https://doi.org/10.1038/s41598-026-36341-4
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