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Low tumoral Trefoil Factor 1 expression relates to aggressive tumor features and poor survival in young women with breast cancer

Abstract In young breast cancer (BC) patients, there is a need for additional biomarkers beyond those currently available. Trefoil Factor 1 (TFF1) is an estrogen-regulated protein with proposed prognostic relevance in BC. We assessed TFF1 protein expression by immunohistochemistry (IHC) in biopsies...

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Principais autores: Amalie B. Kvamme, Ulrikke Hugaas, Anna K. M. Sæle, Lise M. Ingebriktsen, Amalie A. Svanøe, Rasmus O. C. Humlevik, Ingeborg Winge, Turid Aas, Anette Heie, Lars A. Akslen, Erling A. Hoivik, Elisabeth Wik
格式: Artigo
语言:Inglês
出版: Nature Portfolio 2026-01-01
丛编:Scientific Reports
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在线阅读:https://doi.org/10.1038/s41598-026-36341-4
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