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Tumor necrosis associates with aggressive breast cancer features, increased hypoxia signaling and reduced patient survival

Abstract In the growing tumor, hypoxia may lead to tumor necrosis which is associated with more aggressive tumor features and reduced patient survival. However, there are shortcomings in our understanding of biological features and clinical significance linked to tumor necrosis. We therefore analyze...

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Autori principali: Astrid A. Syrtveit, Lise M. Ingebriktsen, Amalie F. Tegnander, Lars A. Akslen, Elisabeth Wik, Erling A. Hoivik
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2025-11-01
Serie:Scientific Reports
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Accesso online:https://doi.org/10.1038/s41598-025-29905-3
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