Tumor necrosis associates with aggressive breast cancer features, increased hypoxia signaling and reduced patient survival

Abstract In the growing tumor, hypoxia may lead to tumor necrosis which is associated with more aggressive tumor features and reduced patient survival. However, there are shortcomings in our understanding of biological features and clinical significance linked to tumor necrosis. We therefore analyze...

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Hlavní autoři:	Astrid A. Syrtveit, Lise M. Ingebriktsen, Amalie F. Tegnander, Lars A. Akslen, Elisabeth Wik, Erling A. Hoivik
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2025-11-01
Edice:	Scientific Reports
Témata:	Breast Cancer Necrosis Signature Score Proliferation Stemness Hypoxia
On-line přístup:	https://doi.org/10.1038/s41598-025-29905-3
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