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Tumor necrosis associates with aggressive breast cancer features, increased hypoxia signaling and reduced patient survival

Abstract In the growing tumor, hypoxia may lead to tumor necrosis which is associated with more aggressive tumor features and reduced patient survival. However, there are shortcomings in our understanding of biological features and clinical significance linked to tumor necrosis. We therefore analyze...

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Principais autores: Astrid A. Syrtveit, Lise M. Ingebriktsen, Amalie F. Tegnander, Lars A. Akslen, Elisabeth Wik, Erling A. Hoivik
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Portfolio 2025-11-01
Colecção:Scientific Reports
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Acesso em linha:https://doi.org/10.1038/s41598-025-29905-3
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