Elevated expression of Aurora-A/AURKA in breast cancer associates with younger age and aggressive features

Abstract Background and objective Aurora kinase A (AURKA) is reported to be overexpressed in breast cancer. In addition to its role in regulating cell cycle and mitosis, studies have reported AURKA involvements in oncogenic signaling in suppressing BRCA1 and BRCA2. We aimed to characterize AURKA pro...

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Hauptverfasser:	L. M. Ingebriktsen, R. O. C. Humlevik, A. A. Svanøe, A. K. M. Sæle, I. Winge, K. Toska, M. B. Kalvenes, B. Davidsen, A. Heie, G. Knutsvik, C. Askeland, I. M. Stefansson, E. A. Hoivik, L. A. Akslen, E. Wik
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2024-08-01
Schriftenreihe:	Breast Cancer Research
Online-Zugang:	https://doi.org/10.1186/s13058-024-01882-x
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