The notch pathway promotes NF-κB activation through Asb2 in T cell acute lymphoblastic leukemia cells
Abstract Background Oncogenic Notch1 is known to activate the NF-κB pathway in T cell acute lymphoblastic leukemia (T-ALL) and to up-regulate the transcription of Asb2α, a specificity factor for an E3 ubiquitin ligase complex that plays an important role in hematopoietic differentiation. Therefore,...
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| Principais autores: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BMC
2018-08-01
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| Colecção: | Cellular & Molecular Biology Letters |
| Assuntos: | |
| Acesso em linha: | http://link.springer.com/article/10.1186/s11658-018-0102-4 |
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